Spontaneous Unilateral Carotid Dissection: A Case Report of a Rare Complication in a Patient With Graves' Disease

Carotid artery dissection (CAD) is a recognized cause of ischemic stroke (IS) in young adults. At the same time, hyperthyroidism, particularly in the context of thyroid storm (TS), can also lead to IS through mechanisms related and unrelated to atrial fibrillation (AF). However, the coexistence of CAD and thyrotoxicosis is extremely rare. We report the case of a 45-year-old woman with Graves' disease (GD) who presented with TS, developing IS secondary to left CAD. The patient had a history of poorly controlled hyperthyroidism despite being on methimazole and beta-blocker therapy. Upon admission, she presented with fever, diarrhea, tremor, and palpitations. Physical examination revealed bilateral exophthalmos, goiter, and AF. Thyroid function tests confirmed TS, and treatment was initiated with antithyroid drugs, betablockers, glucocorticoids, and plasma exchange. Three days later, she developed focal neurological symptoms, and imaging studies revealed multiple ischemic lesions in the left middle cerebral artery territory. Further investigation confirmed left internal CAD, with no evidence of trauma or other underlying conditions to explain the dissection, leading to the conclusion that GD was the likely cause. The patient underwent thyroidectomy with subsequent clinical improvement, and she was discharged in good condition with long-term anticoagulation due to the presence of AF. This case highlights a rare association between GD and CAD, emphasizing the importance of cons

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XRWLeS

Hydrophobic deep eutectic solvents (HDES) are emerging as sustainable and tunable alter­ natives to conventional organic solvents due to their low toxicity, environmental compat­ ibility, and adjustable physicochemical properties. This study investigated the influence of hydrogen-bond donor type on the structure, surface properties, antibacterial activity, and extraction performance of menthol-based HDES, assessing their potential for environmen­ tal remediation. Five HDES were synthesized using levulinic acid, acetic acid, lactic acid, oleic acid, and linalool as hydrogen-bond donors and characterized by nuclear magnetic resonance and infrared spectroscopy. Quantum-chemical calculations predicted donor re­ activity and hydrogen-bonding interactions. Surface properties, including interfacial ten­ sion, contact angles, drop volume, and surface energy components, were measured, and polarity was determined using a solvatochromic probe. Antibacterial activity was tested against Gram-positive and Gram-negative bacteria and Candida species. Extraction effi­ ciency of methylene blue and diclofenac from aqueous solutions was evaluated to assess pollutant removal. The HDES exhibited low interfacial tension and dispersive-dominated surface energy, confirming their hydrophobic nature. Polarity was tunable according to hydrogen-bond donor type, with menthol–linalool HDES showing the strongest antibac­ terial activity. Extraction efficiencies ranged from 65 to 84% for methylene blue and 7 to 52% for diclofenac, highlighting the importance of donor selection, polarity, and vis­ cosity. Greenness evaluation using BAGI and ComplexGAPI tools confirmed superior environmental performance of the synthesized HDES. Menthol-based HDES thus provide multifunctional properties, combining tunable polarity, bioactivity, and efficient pollutant extra ction. They represent a promising class of environmentally friendly solvents for water purification, analytical applications, and sustainable chemical processes. Highlights ● Menthol-based HDES were synthesized using five hydrogen bond donors. ● The HDES exhibited low interfacial tension and dispersive surface energy. ● Solvent polarity was tuned by selecting hydrogen bond donors (ENR ≈ 52–57 kcal/mol). ● Menthol–linalool HDES showed the strongest antibacterial activity. 1 3 V. Vorobyova et al. ● The HDES efficiently extracted methylene blue and diclofenac.

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High-efficiency design and optimization of 2 T monolithic polymer/polymer tandem solar cells using SCAPS-1D simulations

Inthisstudy,wepresentanovel2 Tmonolithicpolymer/polymertandemsolarcell(TSC)modelbasedon experimentallyvalidatedsub-celldesignscomposedentirelyofOSC/OSCpolymers.Theindividualsubcellshavebeencalibratedagainstexperimentaldata,resultinginpowerconversionefficiencies(PCE)of 10.33%forthefrontcelland21.72%forthebackcell.ThelowercellcontainsaPM6:Y6activelayerinan ITO/Cu2O/PM6:Y6/SnO2/Agconfiguration,whiletheupperpolymercellisdesignedwithaconventional ITO/PEDOT:PSS/PM7:PIDT/PDINN/Agstructure,withPM7:PIDTastheabsorberlayer.Simulations wereperformedusingthe1DSCAPStooltoindividuallyoptimizetheperformanceofeachsub-cell. Extensiveinvestigationwascarriedoutonbandalignment,defectdensity,activelayerthicknessandthe selectionofelectronandholetransportlayers(ETLsandHTLs).Theeffectso ftemperature,shuntresistance andseriesresistanceonthetwosub-cellswerealsoanalyzedtoimprovestabilityandperformance.The resultingtandemstructureexhibitedashortcircuitcurrentdensity(JSC)of11.685 mA cm−2,anopencircuit voltage(VOC)of2.0721 V,afillfactorof82.823%andaPCEof20.054%,positioningitasapromising candidateforflexible,greenandhighlyefficienttandemsolarcells.Theseresultshighlightthepotentialof ourdesigntoadvancetheperformancebenchmarksoforganictandemsolarcells. Nomenclature table with units. Nomenclature Meaning Units HTL Hole Transport Layer ETL Electron Transport Layer Eg Energy Bandgap (eV) χ Electron Affinity (eV) ε Relative Permittivity Nc Effective Density of States in Conduction Band (1/cm3) Nv Effective Density of

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Study on the uranium adsorption and reusability characteristics of amidoximated polypropylene‑acrylonitrile‑acrylic acid fibrous adsorbent

The kinetics and thermodynamics of the U(VI) adsorption process on amidoximated polypropylene-acrylonitrile-acrylic acid (AOPP-AN-AAc) fiber adsorbent were investigated by static adsorption at different temperatures. The process of uranium adsorption by the adsorbent was fitted to the pseudo-second-order kinetic model and the pseudo-second-order rate constant and the pseudo activation energy at different temperatures were determined. The thermodynamic properties of the U(VI) adsorption process by the adsorbent were also evaluated. The optimum conditions of adsorption were determined by studying the effects of U(VI) concentration, solution pH, temperature and stirring conditions on the adsorption equilibrium. The desorption and regeneration properties of U(VI) adsorb ed on the adsorbent were evaluated in different media.

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Biosynthesis Optimization of Antibacterial‑Magnetic Iron Oxide Nanoparticles from Bacillus megaterium

The occurrence of antibiotic resistance on common bacterial agents and the need to use new generations of antibiotics have led to the use of various strategies for production. Taking inspiration from nature, using bio-imitation patterns, in addition to the low cost of production, is advantageous and highly accurate. In this research, we were able to control the temperature, shake, and synthesis time of the synthesis conditions of Bacillus megaterium bacteria as a model for the synthesis of magnetic iron nanoparticles and optimize the ratio of reducing salt to bacterial regenerating agents as well as the concentration of salt to create iron oxide nanoparticles with more favorable properties and produced with more antibacterial properties. Bacterial growth was in vestigated by changing the incubation times of pre-culture and overnight culture in the range of the logarithmic phase. The synthesis time, salt ratio, and concentration were optimized to achieve the size, charge, colloidal stability, and magnetic and antibacterial properties of nanoparticles. The amount of the effective substance produced by the bacteria was selected by measuring the amount of the active substance synthesized using the free radical reduction (DPPH) method. With the help of DPPH, the duration of the synthesis was determined to be one week. Characterizations such as UV–vis spectroscopy, FTIR, FESEM, X-ray, and scattering optical dynamics were performed and showed that the nanoparticles synthesized with a salt concentration of 80 mM and a bacterial suspension to salt ratio of 2:1 are smaller in size and have a light scattering index, a PDI index close to 0.1, and a greater amount of reducing salt used in the reaction during one week compared to other samples. Moreov er, they had more antibacterial properties than the concentration of 100 mM. As a result, better characteristics and more antibacterial properties than common antibiotics were created on E. coli and Bacillus cereus.

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[¹⁷⁷Lu]Lu-DOTA-TATE plus long-acting octreotide versus high‑dose long-acting octreotide for the treatment of newly diagnosed, advanced grade 2–3, well-differentiated, gastroenteropancreatic neuroendocrine tumours (NETTER-2): an open-label, randomised, phase 3 study

(Abstract not found)

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Comparison of Robotics and Navigation for Clinical Outcomes After Minimally Invasive Lumbar Fusion

(Abstract not found)

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